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Dual Role of Integrin Alpha-6 in Glioblastoma: Supporting Stemness in Proneural Stem-Like Cells While Inducing Radioresistance in Mesenchymal Stem-Like Cells

SIMPLE SUMMARY: Glioblastoma stem-like cells (GSCs) are responsible for most of the malignant characteristics of glioblastoma, including therapeutic resistance, tumour recurrence, and tumour cellular heterogeneity. Therefore, increased understanding of the mechanisms regulating GSCs aggressiveness m...

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Detalles Bibliográficos
Autores principales: Stanzani, Elisabetta, Pedrosa, Leire, Bourmeau, Guillaume, Anezo, Oceane, Noguera-Castells, Aleix, Esteve-Codina, Anna, Passoni, Lorena, Matteoli, Michela, de la Iglesia, Núria, Seano, Giorgio, Martínez-Soler, Fina, Tortosa, Avelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235627/
https://www.ncbi.nlm.nih.gov/pubmed/34205341
http://dx.doi.org/10.3390/cancers13123055