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Renal Safety of [(177)Lu]Lu-PSMA-617 Radioligand Therapy in Patients with Compromised Baseline Kidney Function

SIMPLE SUMMARY: Radioligand therapy (RLT) targeting prostate-specific membrane antigen (PSMA) is an effective antitumor-treatment in metastatic castration-resistant prostate carcinoma (mCRPC). Concerns of potential nephrotoxicity are based on renal tubular PSMA expression and the resulting radiophar...

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Detalles Bibliográficos
Autores principales: Rosar, Florian, Kochems, Niklas, Bartholomä, Mark, Maus, Stephan, Stemler, Tobias, Linxweiler, Johannes, Khreish, Fadi, Ezziddin, Samer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235711/
https://www.ncbi.nlm.nih.gov/pubmed/34205686
http://dx.doi.org/10.3390/cancers13123095