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Inhibition of Oxidative Stress and ALOX12 and NF-κB Pathways Contribute to the Protective Effect of Baicalein on Carbon Tetrachloride-Induced Acute Liver Injury

This study investigates the protective effect of baicalein on carbon tetrachloride (CCl(4))-induced acute liver injury and the underlying molecular mechanisms. Mice were orally administrated baicalein at 25 and 100 mg/kg/day for 7 consecutive days or ferrostatin-1 (Fer-1) at 10 mg/kg was i.p. inject...

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Detalles Bibliográficos
Autores principales: Dai, Chongshan, Li, Hui, Wang, Yang, Tang, Shusheng, Velkov, Tony, Shen, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235740/
https://www.ncbi.nlm.nih.gov/pubmed/34207230
http://dx.doi.org/10.3390/antiox10060976