Kinase Inhibitors of DNA-PK, ATM and ATR in Combination with Ionizing Radiation Can Increase Tumor Cell Death in HNSCC Cells While Sparing Normal Tissue Cells

(1) Kinase inhibitors (KI) targeting components of the DNA damage repair pathway are a promising new type of drug. Combining them with ionizing radiation therapy (IR), which is commonly used for treatment of head and neck tumors, could improve tumor control, but could also increase negative side eff...

Descripción completa

Detalles Bibliográficos
Autores principales: Faulhaber, Eva-Maria, Jost, Tina, Symank, Julia, Scheper, Julian, Bürkel, Felix, Fietkau, Rainer, Hecht, Markus, Distel, Luitpold V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235750/
https://www.ncbi.nlm.nih.gov/pubmed/34204447
http://dx.doi.org/10.3390/genes12060925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235750/
https://www.ncbi.nlm.nih.gov/pubmed/34204447
http://dx.doi.org/10.3390/genes12060925

Ejemplares similares