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The N-Formyl Peptide Receptor 2 (FPR2) Agonist MR-39 Exhibits Anti-Inflammatory Activity in LPS-Stimulated Organotypic Hippocampal Cultures

Accumulating evidence indicates a pivotal role for chronic inflammatory processes in the pathogenesis of neurodegenerative and psychiatric disorders. G protein-coupled formyl peptide receptor 2 (FPR2) mediates pro-inflammatory or anti-/pro-resolving effects upon stimulation with biased agonists. We...

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Detalles Bibliográficos
Autores principales: Trojan, Ewa, Tylek, Kinga, Leśkiewicz, Monika, Lasoń, Władysław, Brandenburg, Lars-Ove, Leopoldo, Marcello, Lacivita, Enza, Basta-Kaim, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235773/
https://www.ncbi.nlm.nih.gov/pubmed/34204273
http://dx.doi.org/10.3390/cells10061524