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Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression

BACKGROUND: Mesothelial E- and P-selectins substantially mediate the intraperitoneal spread of Pancreatic ductal adenocarcinoma (PDA) cells in xenograft models. In the absence of selectins in the host, the integrin subunit alpha-V (ITGAV, CD51) was upregulated in the remaining metastatic deposits. H...

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Detalles Bibliográficos
Autores principales: Kemper, Marius, Schiecke, Alina, Maar, Hanna, Nikulin, Sergey, Poloznikov, Andrey, Galatenko, Vladimir, Tachezy, Michael, Gebauer, Florian, Lange, Tobias, Riecken, Kristoffer, Tonevitsky, Alexander, Aigner, Achim, Izbicki, Jakob, Schumacher, Udo, Wicklein, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235815/
https://www.ncbi.nlm.nih.gov/pubmed/34174926
http://dx.doi.org/10.1186/s13046-021-01946-2