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Recommendations for designing and analysing multi-arm non-inferiority trials: a review of methodology and current practice
BACKGROUND AND PURPOSE: Multi-arm non-inferiority (MANI) trials, here defined as non-inferiority trials with multiple experimental treatment arms, can be useful in situations where several viable treatments exist for a disease area or for testing different dose schedules. To maintain the statistical...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235859/ https://www.ncbi.nlm.nih.gov/pubmed/34174937 http://dx.doi.org/10.1186/s13063-021-05364-9 |