Cargando…
Recommendations for designing and analysing multi-arm non-inferiority trials: a review of methodology and current practice
BACKGROUND AND PURPOSE: Multi-arm non-inferiority (MANI) trials, here defined as non-inferiority trials with multiple experimental treatment arms, can be useful in situations where several viable treatments exist for a disease area or for testing different dose schedules. To maintain the statistical...
Autores principales: | Emmerson, Jake, Todd, Susan, Brown, Julia M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235859/ https://www.ncbi.nlm.nih.gov/pubmed/34174937 http://dx.doi.org/10.1186/s13063-021-05364-9 |
Ejemplares similares
-
Adding a treatment arm to an ongoing clinical trial: a review of methodology and practice
por: Cohen, Dena R, et al.
Publicado: (2015) -
Some recommendations for multi-arm multi-stage trials
por: Wason, James, et al.
Publicado: (2012) -
Screening for Hypertension in Children and Adolescents: Methodology and Current Practice Recommendations
por: Lewis, Michaela N., et al.
Publicado: (2017) -
Flexible trial design in practice – dropping and adding arms in STAMPEDE: a multi-arm multi-stage randomised controlled trial
por: Sydes, Matthew R, et al.
Publicado: (2011) -
Flexible trial design in practice - stopping arms for lack-of-benefit and adding research arms mid-trial in STAMPEDE: a multi-arm multi-stage randomized controlled trial
por: Sydes, Matthew R, et al.
Publicado: (2012)