Mechanism of Nucleic Acid Sensing in Retinal Pigment Epithelium (RPE): RIG-I Mediates Type I Interferon Response in Human RPE

Age-related macular degeneration (AMD), a degenerative disease of the outer retina, is the leading cause of blindness among the elderly. A hallmark of geographic atrophy (GA), an advanced type of nonneovascular AMD (dry AMD), is photoreceptor and retinal pigment epithelium (RPE) cell death. Currentl...

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Detalles Bibliográficos
Autores principales: Schustak, Joshua, Twarog, Michael, Wu, Xiaoqiu, Wu, Henry Y., Huang, Qian, Bao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235977/
https://www.ncbi.nlm.nih.gov/pubmed/34239945
http://dx.doi.org/10.1155/2021/9975628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8235977/
https://www.ncbi.nlm.nih.gov/pubmed/34239945
http://dx.doi.org/10.1155/2021/9975628

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