Aberrant MCM10 SUMOylation induces genomic instability mediated by a genetic variant associated with survival of esophageal squamous cell carcinoma

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the common gastrointestinal malignancy with an inferior prognosis outcome. DNA replication licensing aberration induced by dysregulation of minichromosome maintenance proteins (MCMs) causes genomic instability and cancer metastasis. SUM...

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Detalles Bibliográficos
Autores principales: Tian, Jianbo, Lu, Zequn, Niu, Siyuan, Zhang, Shanshan, Ying, Pingting, Wang, Lu, Zhang, Ming, Cai, Yimin, Dong, Tianyi, Zhu, Ying, Zhong, Rong, Wang, Zhihua, Chang, Jiang, Miao, Xiaoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236122/
https://www.ncbi.nlm.nih.gov/pubmed/34185429
http://dx.doi.org/10.1002/ctm2.485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236122/
https://www.ncbi.nlm.nih.gov/pubmed/34185429
http://dx.doi.org/10.1002/ctm2.485

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