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Circ-ACTR2 aggravates the high glucose-induced cell dysfunction of human renal mesangial cells through mediating the miR-205-5p/HMGA2 axis in diabetic nephropathy

BACKGROUND: Circular RNAs (circRNAs) have been considered as pivotal biomarkers in Diabetic nephropathy (DN). CircRNA ARP2 actin-related protein 2 homolog (circ-ACTR2) could promote the HG-induced cell injury in DN. However, how circ-ACTR2 acts in DN is still unclear. This study aimed to explore the...

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Detalles Bibliográficos
Autores principales: Yun, Jie, Ren, Jinyu, Liu, Yufei, Dai, Lijuan, Song, Liqun, Ma, Xiaopeng, Luo, Shan, Song, Yexu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236153/
https://www.ncbi.nlm.nih.gov/pubmed/34174955
http://dx.doi.org/10.1186/s13098-021-00692-x