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Understanding and Monitoring Chronic Myeloid Leukemia Blast Crisis: How to Better Manage Patients

Chronic myeloid leukemia (CML) is triggered primarily by the t(9;22) (q34.13; q11.23) translocation. This reciprocal chromosomal translocation leads to the formation of the BCR-ABL fusion gene. Patients in the chronic phase (CP) experience a good curative effect with tyrosine kinase inhibitors. Howe...

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Detalles Bibliográficos
Autores principales: Wang, Lulu, Li, Li, Chen, Rongrong, Huang, Xianbo, Ye, Xiujin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236273/
https://www.ncbi.nlm.nih.gov/pubmed/34188552
http://dx.doi.org/10.2147/CMAR.S314343