Serum IGF1 and linear growth in children with congenital leptin deficiency before and after leptin substitution

BACKGROUND: Evidence from in vitro and rodent studies suggests that leptin, a key signal of long-term energy reserves, promotes IGF1 synthesis and linear growth. This effect of leptin has not been fully investigated in humans. The aim of our study was to investigate the effect of leptin substitution...

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Detalles Bibliográficos
Autores principales: Beghini, Marianna, Brandt, Stephanie, Körber, Ingrid, Kohlsdorf, Katja, Vollbach, Heike, Lennerz, Belinda, Denzer, Christian, Shalitin, Shlomit, Santini, Ferruccio, Blum, Werner F., von Schnurbein, Julia, Wabitsch, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236407/
https://www.ncbi.nlm.nih.gov/pubmed/34002033
http://dx.doi.org/10.1038/s41366-021-00809-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236407/
https://www.ncbi.nlm.nih.gov/pubmed/34002033
http://dx.doi.org/10.1038/s41366-021-00809-2

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