Risk factors mediating the effect of body mass index and waist-to-hip ratio on cardiovascular outcomes: Mendelian randomization analysis

BACKGROUND: Higher body mass index (BMI) and waist-to-hip ratio (WHR) increase the risk of cardiovascular disease, but the extent to which this is mediated by blood pressure, diabetes, lipid traits, and smoking is not fully understood. METHODS: Using consortia and UK Biobank genetic association summ...

Descripción completa

Detalles Bibliográficos
Autores principales: Gill, Dipender, Zuber, Verena, Dawson, Jesse, Pearson-Stuttard, Jonathan, Carter, Alice R., Sanderson, Eleanor, Karhunen, Ville, Levin, Michael G., Wootton, Robyn E., Klarin, Derek, Tsao, Philip S., Tsilidis, Konstantinos K., Damrauer, Scott M., Burgess, Stephen, Elliott, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236409/
https://www.ncbi.nlm.nih.gov/pubmed/34002035
http://dx.doi.org/10.1038/s41366-021-00807-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236409/
https://www.ncbi.nlm.nih.gov/pubmed/34002035
http://dx.doi.org/10.1038/s41366-021-00807-4

Ejemplares similares