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Rationale and Design of Assessing the Effectiveness of Short-Term Low-Dose Lithium Therapy in Averting Cardiac Surgery-Associated Acute Kidney Injury: A Randomized, Double Blinded, Placebo Controlled Pilot Trial

Background: Burgeoning pre-clinical evidence suggests that therapeutic targeting of glycogen synthase kinase 3β (GSK3β), a convergence point of multiple cellular protective signaling pathways, confers a beneficial effect on acute kidney injury (AKI) in experimental models. However, it remains unknow...

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Detalles Bibliográficos
Autores principales: Sharif, Sairah, Chen, Bohan, Brewster, Pamela, Chen, Tian, Dworkin, Lance, Gong, Rujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236527/
https://www.ncbi.nlm.nih.gov/pubmed/34195206
http://dx.doi.org/10.3389/fmed.2021.639402