Canine Transforming Growth Factor-β Receptor 2-Ig: A Potential Candidate Biologic for Melanoma Treatment That Reverses Transforming Growth Factor-β1 Immunosuppression

Cancer cells can evade host immune systems via multiple mechanisms. Transforming growth factor beta 1 (TGF-β1) is an immunosuppressive cytokine that induces regulatory T cell (Tregs) differentiation and is involved in immune evasion mechanisms in cancer. The inhibition of the TGF-β1 signaling pathwa...

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Detalles Bibliográficos
Autores principales: Takeuchi, Hiroto, Konnai, Satoru, Maekawa, Naoya, Takagi, Satoshi, Ohta, Hiroshi, Sasaki, Noboru, Kim, Sangho, Okagawa, Tomohiro, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Veterinary Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236594/
https://www.ncbi.nlm.nih.gov/pubmed/34195245
http://dx.doi.org/10.3389/fvets.2021.656715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236594/
https://www.ncbi.nlm.nih.gov/pubmed/34195245
http://dx.doi.org/10.3389/fvets.2021.656715

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