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Canine Transforming Growth Factor-β Receptor 2-Ig: A Potential Candidate Biologic for Melanoma Treatment That Reverses Transforming Growth Factor-β1 Immunosuppression

Cancer cells can evade host immune systems via multiple mechanisms. Transforming growth factor beta 1 (TGF-β1) is an immunosuppressive cytokine that induces regulatory T cell (Tregs) differentiation and is involved in immune evasion mechanisms in cancer. The inhibition of the TGF-β1 signaling pathwa...

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Detalles Bibliográficos
Autores principales:	Takeuchi, Hiroto, Konnai, Satoru, Maekawa, Naoya, Takagi, Satoshi, Ohta, Hiroshi, Sasaki, Noboru, Kim, Sangho, Okagawa, Tomohiro, Suzuki, Yasuhiko, Murata, Shiro, Ohashi, Kazuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Veterinary Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236594/ https://www.ncbi.nlm.nih.gov/pubmed/34195245 http://dx.doi.org/10.3389/fvets.2021.656715

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