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Characterization of Human Genes Modulated by Porphyromonas gingivalis Highlights the Ribosome, Hypothalamus, and Cholinergic Neurons

Porphyromonas gingivalis, a bacterium associated with periodontal disease, is a suspected cause of Alzheimer’s disease. This bacterium is reliant on gingipain proteases, which cleave host proteins after arginine and lysine residues. To characterize gingipain susceptibility, we performed enrichment a...

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Detalles Bibliográficos
Autores principales: Patel, Sejal, Howard, Derek, Chowdhury, Nityananda, Derieux, Casey, Wellslager, Bridgette, Yilmaz, Özlem, French, Leon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236716/
https://www.ncbi.nlm.nih.gov/pubmed/34194426
http://dx.doi.org/10.3389/fimmu.2021.646259