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Ras-Related C3 Botulinum Toxin Substrate 1 Combining With the Mixed Lineage Kinase 3- Mitogen-Activated Protein Kinase 7- c-Jun N-Terminal Kinase Signaling Module Accelerates Diabetic Nephropathy

Ras-related C3 botulinum toxin substrate 1 (RAC1) activation plays a vital role in diabetic nephropathy (DN), but the exact mechanism remains unclear. In this study, we attempted to elucidate the precise mechanism of how RAC1 aggravates DN through cellular and animal experiments. In this study, DN w...

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Detalles Bibliográficos
Autores principales: Ying, Changjiang, Dai, Jiao, Fan, Gaoxia, Zhou, Zhongyuan, Gan, Tian, Zhang, Yusheng, Song, Yuanjian, Zhou, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236718/
https://www.ncbi.nlm.nih.gov/pubmed/34194338
http://dx.doi.org/10.3389/fphys.2021.679166