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Highly prevalent Russian HIV-1 V3-loop sequence variants are susceptible to maraviroc

INTRODUCTION: Maraviroc inhibits CCR5-tropic HIV-1 across different subtypes in vitro and has demonstrated efficacy in clinical trials. V3-loop amino acid variants observed in individual maraviroc-resistant viruses have not been found to be predictive of reduced susceptibility. Sequence-database sea...

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Detalles Bibliográficos
Autores principales: Lewis, ME, Jubb, B, Simpson, P, Lopatukhin, A, Kireev, D, Bobkova, M, Craig, C, van der Ryst, E, Westby, M, Butler, SL
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236768/
https://www.ncbi.nlm.nih.gov/pubmed/34160290
http://dx.doi.org/10.1177/20402066211025156