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Highly prevalent Russian HIV-1 V3-loop sequence variants are susceptible to maraviroc
INTRODUCTION: Maraviroc inhibits CCR5-tropic HIV-1 across different subtypes in vitro and has demonstrated efficacy in clinical trials. V3-loop amino acid variants observed in individual maraviroc-resistant viruses have not been found to be predictive of reduced susceptibility. Sequence-database sea...
Autores principales: | Lewis, ME, Jubb, B, Simpson, P, Lopatukhin, A, Kireev, D, Bobkova, M, Craig, C, van der Ryst, E, Westby, M, Butler, SL |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236768/ https://www.ncbi.nlm.nih.gov/pubmed/34160290 http://dx.doi.org/10.1177/20402066211025156 |
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