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The Rho kinase signaling pathway participates in tubular mitochondrial oxidative injury and apoptosis in uric acid nephropathy

INTRODUCTION: Oxidative stress is a pathologic feature of hyperuricemia that is highly prevalent and that contributes to kidney tubular interstitial fibrosis. Rho-kinase is closely related to mitochondrial-induced oxidative stress. Herein, we designed a study to explore the expression and role of Rh...

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Detalles Bibliográficos
Autores principales: Su, Yan, Hu, Langtao, Wang, Yanni, Ying, Gangqiang, Ma, Chunyang, Wei, Jiali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236795/
https://www.ncbi.nlm.nih.gov/pubmed/34167354
http://dx.doi.org/10.1177/03000605211021752