A Repurposed Drug Screen Identifies Compounds That Inhibit the Binding of the COVID-19 Spike Protein to ACE2

Repurposed drugs that block the interaction between the SARS-CoV-2 spike protein and its receptor ACE2 could offer a rapid route to novel COVID-19 treatments or prophylactics. Here, we screened 2,701 compounds from a commercial library of drugs approved by international regulatory agencies for their...

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Detalles Bibliográficos
Autores principales: Tsegay, Kaleb B., Adeyemi, Christiana M., Gniffke, Edward P., Sather, D. Noah, Walker, John K., Smith, Stephen E. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236845/
https://www.ncbi.nlm.nih.gov/pubmed/34194331
http://dx.doi.org/10.3389/fphar.2021.685308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8236845/
https://www.ncbi.nlm.nih.gov/pubmed/34194331
http://dx.doi.org/10.3389/fphar.2021.685308

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