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ADAMTS13 regulation of VWF multimer distribution in severe COVID‐19

BACKGROUND: Consistent with fulminant endothelial cell activation, elevated plasma von Willebrand factor (VWF) antigen levels have been reported in patients with COVID‐19. The multimeric size and function of VWF are normally regulated through A Disintegrin And Metalloprotease with ThrombSpondin Moti...

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Detalles Bibliográficos
Autores principales: Ward, Soracha E., Fogarty, Helen, Karampini, Ellie, Lavin, Michelle, Schneppenheim, Sonja, Dittmer, Rita, Morrin, Hannah, Glavey, Siobhan, Ni Cheallaigh, Cliona, Bergin, Colm, Martin‐Loeches, Ignacio, Mallon, Patrick W., Curley, Gerard F., Baker, Ross I., Budde, Ulrich, O’Sullivan, Jamie M., O’Donnell, James S., O’Connell, Niamh, Byrne, Mary, Townsend, Liam, McEvoy, Natalie L., Clarke, Jennifer, Boylan, Maria, Alalqam, Razi, Worrall, Amy P., Kelly, Claire, de Barra, Eoghan, Preston, Roger, Kenny, Dermot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Journal of Thrombosis and Haemostasis published by ELSEVIER INC. on behalf of International Society on Thrombosis and Haemostasis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237059/
https://www.ncbi.nlm.nih.gov/pubmed/34053187
http://dx.doi.org/10.1111/jth.15409