Investigating the response of paediatric leukaemia‐propagating cells to BCL‐2 inhibitors

Relapse of paediatric acute lymphoblastic leukaemia (ALL) may occur due to persistence of resistant cells with leukaemia‐propagating ability (LPC). In leukaemia, the balance of B‐cell lymphoma‐2 (BCL‐2) family proteins is disrupted, promoting survival of malignant cells and possibly LPC. A direct co...

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Detalles Bibliográficos
Autores principales: Diamanti, Paraskevi, Ede, Benjamin C., Dace, Phoebe EI, Barendt, William J., Cox, Charlotte V., Hancock, Jeremy P., Moppett, John P., Blair, Allison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Haematological Malignancy ‐ Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237230/
https://www.ncbi.nlm.nih.gov/pubmed/32452017
http://dx.doi.org/10.1111/bjh.16773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237230/
https://www.ncbi.nlm.nih.gov/pubmed/32452017
http://dx.doi.org/10.1111/bjh.16773

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