Uncarboxylated osteocalcin promotes osteogenesis and inhibits adipogenesis of mouse bone marrow-derived mesenchymal stem cells via the PKA-AMPK-SIRT1 axis

Osteoporosis is a bone disease characterized by reduced bone density, thin cortical bone and large gaps in the bone's honeycomb structure, which increases the risk of bone fragility. Uncarboxylated osteocalcin (unOC), a vitamin K-dependent bone protein, is known to regulate carbohydrate and ene...

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Detalles Bibliográficos
Autores principales: Gao, Le, Gong, Fang-Zi, Ma, Lu-Yao, Yang, Jian-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237271/
https://www.ncbi.nlm.nih.gov/pubmed/34194558
http://dx.doi.org/10.3892/etm.2021.10312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237271/
https://www.ncbi.nlm.nih.gov/pubmed/34194558
http://dx.doi.org/10.3892/etm.2021.10312

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