A novel imidazolinone metformin‐methylglyoxal metabolite promotes endothelial cell angiogenesis via the eNOS/HIF‐1α pathway

Peripheral arterial disease (PAD) is one of the major complications of diabetes due to an impairment in angiogenesis. Since there is currently no drug with satisfactory efficacy to enhance blood vessel formation, discovering therapies to improve angiogenesis is critical. An imidazolinone metabolite...

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Detalles Bibliográficos
Autores principales: Nguyen, Huong, Koh, Jia Yi, Li, Hainan, Islas‐Robles, Argel, Meda Venkata, Sai Pranathi, Wang, Jie‐Mei, Monks, Terrence J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237315/
https://www.ncbi.nlm.nih.gov/pubmed/34105824
http://dx.doi.org/10.1096/fj.202002674RR

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237315/
https://www.ncbi.nlm.nih.gov/pubmed/34105824
http://dx.doi.org/10.1096/fj.202002674RR

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