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A novel imidazolinone metformin‐methylglyoxal metabolite promotes endothelial cell angiogenesis via the eNOS/HIF‐1α pathway
Peripheral arterial disease (PAD) is one of the major complications of diabetes due to an impairment in angiogenesis. Since there is currently no drug with satisfactory efficacy to enhance blood vessel formation, discovering therapies to improve angiogenesis is critical. An imidazolinone metabolite...
Autores principales: | Nguyen, Huong, Koh, Jia Yi, Li, Hainan, Islas‐Robles, Argel, Meda Venkata, Sai Pranathi, Wang, Jie‐Mei, Monks, Terrence J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237315/ https://www.ncbi.nlm.nih.gov/pubmed/34105824 http://dx.doi.org/10.1096/fj.202002674RR |
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