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Early induction of hepatic deiodinase type 1 inhibits hepatosteatosis during NAFLD progression

OBJECTIVE: Nonalcoholic fatty liver disease (NAFLD) comprises a spectrum ranging from hepatosteatosis to progressive nonalcoholic steatohepatitis that can lead to cirrhosis. Humans with low levels of prohormone thyroxine (T(4)) have a higher incidence of NAFLD, and thyroid hormone treatment is very...

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Detalles Bibliográficos
Autores principales: Bruinstroop, Eveline, Zhou, Jin, Tripathi, Madhulika, Yau, Winifred W., Boelen, Anita, Singh, Brijesh Kumar, Yen, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237360/
https://www.ncbi.nlm.nih.gov/pubmed/34098145
http://dx.doi.org/10.1016/j.molmet.2021.101266