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Early induction of hepatic deiodinase type 1 inhibits hepatosteatosis during NAFLD progression
OBJECTIVE: Nonalcoholic fatty liver disease (NAFLD) comprises a spectrum ranging from hepatosteatosis to progressive nonalcoholic steatohepatitis that can lead to cirrhosis. Humans with low levels of prohormone thyroxine (T(4)) have a higher incidence of NAFLD, and thyroid hormone treatment is very...
Autores principales: | Bruinstroop, Eveline, Zhou, Jin, Tripathi, Madhulika, Yau, Winifred W., Boelen, Anita, Singh, Brijesh Kumar, Yen, Paul M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237360/ https://www.ncbi.nlm.nih.gov/pubmed/34098145 http://dx.doi.org/10.1016/j.molmet.2021.101266 |
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