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HIVIntact: a python-based tool for HIV-1 genome intactness inference

The characterisation of the HIV-1 reservoir, which consists of replication-competent integrated proviruses that persist on antiretroviral therapy (ART), is made difficult by the rarity of intact proviruses relative to those that are defective. While the only conclusive test for the replication-compe...

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Detalles Bibliográficos
Autores principales: Wright, Imogen A., Bale, Michael J., Shao, Wei, Hu, Wei-Shau, Coffin, John M., Van Zyl, Gert U., Kearney, Mary F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237426/
https://www.ncbi.nlm.nih.gov/pubmed/34176496
http://dx.doi.org/10.1186/s12977-021-00561-5