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Gene expression analysis in EBV-infected ataxia-telangiectasia cell lines by RNA-sequencing reveals protein synthesis defect and immune abnormalities

BACKGROUND: Epstein–Barr virus (EBV) targets B-cells where it establishes a latent infection. EBV can transform B-cells in vitro and is recognized as an oncogenic virus, especially in the setting of immune compromise. Indeed, immunodeficient patients may fail to control chronic EBV infection, leadin...

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Detalles Bibliográficos
Autores principales: Tatfi, Moussab, Perthame, Emeline, Hillion, Kenzo-Hugo, Dillies, Marie-Agnès, Menager, Hervé, Hermine, Olivier, Suarez, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237493/
https://www.ncbi.nlm.nih.gov/pubmed/34183044
http://dx.doi.org/10.1186/s13023-021-01904-3