Cargando…
Dental effects of enzyme replacement therapy in case of childhood-type hypophosphatasia
BACKGROUND: Hypophosphatasia (HPP), a skeletal disease characterized by hypomineralization of bone and teeth, is caused by an ALPL gene mutation that leads to low activity of the tissue non-specific alkaline phosphatase enzyme. Although enzyme replacement therapy (ERT) was recently introduced for af...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237502/ https://www.ncbi.nlm.nih.gov/pubmed/34176466 http://dx.doi.org/10.1186/s12903-021-01673-2 |