Self-activation of Vγ9Vδ2 T cells by exogenous phosphoantigens involves TCR and butyrophilins

The high cytotoxic activity of Vγ9Vδ2 T lymphocytes against tumor cells makes them useful candidates in anticancer therapies. However, the molecular mechanism of their activation by phosphoantigens (PAgs) is not completely known. Many studies have depicted the mechanism of Vγ9Vδ2 T-cell activation b...

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Detalles Bibliográficos
Autores principales: Laplagne, Chloé, Ligat, Laetitia, Foote, Juliet, Lopez, Frederic, Fournié, Jean-Jacques, Laurent, Camille, Valitutti, Salvatore, Poupot, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237548/
https://www.ncbi.nlm.nih.gov/pubmed/34183807
http://dx.doi.org/10.1038/s41423-021-00720-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237548/
https://www.ncbi.nlm.nih.gov/pubmed/34183807
http://dx.doi.org/10.1038/s41423-021-00720-w

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