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Disrupted osteocyte connectivity and pericellular fluid flow in bone with aging and defective TGF-β signaling
Skeletal fragility in the elderly does not simply result from a loss of bone mass. However, the mechanisms underlying the concurrent decline in bone mass, quality, and mechanosensitivity with age remain unclear. The important role of osteocytes in these processes and the age-related degeneration of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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National Academy of Sciences
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237574/ https://www.ncbi.nlm.nih.gov/pubmed/34161267 http://dx.doi.org/10.1073/pnas.2023999118 |