Antibody heavy chain CDR3 length-dependent usage of human IGHJ4 and IGHJ6 germline genes

Therapeutic antibody discovery using synthetic diversity has been proved productive, especially for target proteins not suitable for traditional animal immunization-based antibody discovery approaches. Recently, many lines of evidences suggest that the quality of synthetic diversity design limits th...

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Detalles Bibliográficos
Autores principales: Wang, Huimin, Yan, Kai, Wang, Ruixue, Yang, Yi, Shen, Yuelei, Yu, Changyuan, Chen, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237691/
https://www.ncbi.nlm.nih.gov/pubmed/34195544
http://dx.doi.org/10.1093/abt/tbab010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237691/
https://www.ncbi.nlm.nih.gov/pubmed/34195544
http://dx.doi.org/10.1093/abt/tbab010

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