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The E3 Ligase PIAS1 Regulates p53 Sumoylation to Control Stress-Induced Apoptosis of Lens Epithelial Cells Through the Proapoptotic Regulator Bax

Protein sumoylation is one of the most important post-translational modifications regulating many biological processes (Flotho A & Melchior F. 2013. Ann Rev. Biochem. 82:357–85). Our previous studies have shown that sumoylation plays a fundamental role in regulating lens differentiation (Yan et...

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Detalles Bibliográficos
Autores principales: Nie, Qian, Chen, Huimin, Zou, Ming, Wang, Ling, Hou, Min, Xiang, Jia-Wen, Luo, Zhongwen, Gong, Xiao-Dong, Fu, Jia-Ling, Wang, Yan, Zheng, Shu-Yu, Xiao, Yuan, Gan, Yu-Wen, Gao, Qian, Bai, Yue-Yue, Wang, Jing-Miao, Zhang, Lan, Tang, Xiang-Cheng, Hu, Xuebin, Gong, Lili, Liu, Yizhi, Li, David Wan-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237824/
https://www.ncbi.nlm.nih.gov/pubmed/34195189
http://dx.doi.org/10.3389/fcell.2021.660494