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Pharmacogenomic Effects of β-Blocker Use on Femoral Neck Bone Mineral Density

CONTEXT: Recent studies have shown that β-blocker (BB) users have a decreased risk of fracture and higher bone mineral density (BMD) compared to nonusers, likely due to the suppression of adrenergic signaling in osteoblasts, leading to increased BMD. There is also variability in the effect size of B...

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Detalles Bibliográficos
Autores principales: Nevola, Kathleen T, Nagarajan, Archana, Hinton, Alexandra C, Trajanoska, Katerina, Formosa, Melissa M, Xuereb-Anastasi, Angela, van der Velde, Nathalie, Stricker, Bruno H, Rivadeneira, Fernando, Fuggle, Nicholas R, Westbury, Leo D, Dennison, Elaine M, Cooper, Cyrus, Kiel, Douglas P, Motyl, Katherine J, Lary, Christine W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237849/
https://www.ncbi.nlm.nih.gov/pubmed/34195528
http://dx.doi.org/10.1210/jendso/bvab092