Neuroactive venom compounds obtained from Phlogiellus bundokalbo as potential leads for neurodegenerative diseases: insights on their acetylcholinesterase and beta-secretase inhibitory activities in vitro

BACKGROUND: Spider venom is a rich cocktail of neuroactive compounds designed to prey capture and defense against predators that act on neuronal membrane proteins, in particular, acetylcholinesterases (AChE) that regulate synaptic transmission through acetylcholine (ACh) hydrolysis - an excitatory n...

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Detalles Bibliográficos
Autores principales: Lopez, Simon Miguel M., Aguilar, Jeremey S., Fernandez, Jerene Bashia B., Lao, Angelic Gayle J., Estrella, Mitzi Rain R., Devanadera, Mark Kevin P., Ramones, Cydee Marie V., Villaraza, Aaron Joseph L., Guevarra, Leonardo A., Santiago-Bautista, Myla R., Santiago, Librado A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centro de Estudos de Venenos e Animais Peçonhentos (CEVAP/UNESP) 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237997/
https://www.ncbi.nlm.nih.gov/pubmed/34249120
http://dx.doi.org/10.1590/1678-9199-JVATITD-2021-0009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237997/
https://www.ncbi.nlm.nih.gov/pubmed/34249120
http://dx.doi.org/10.1590/1678-9199-JVATITD-2021-0009

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