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Prediction of essential binding domains for the endocannabinoid N-arachidonoylethanolamine (AEA) in the brain cannabinoid CB1 receptor

Δ(9)-tetrahydrocannabinol (Δ(9)-THC), the main active ingredient of Cannabis sativa (marijuana), interacts with the human brain cannabinoid (CB1) receptor and mimics pharmacological effects of endocannabinoids (eCBs) like N-arachidonylethanolamide (AEA). Due to its flexible nature of AEA structure w...

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Detalles Bibliográficos
Autor principal: Shim, Joong-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238219/
https://www.ncbi.nlm.nih.gov/pubmed/34181638
http://dx.doi.org/10.1371/journal.pone.0229879