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Is stem cell transplantation still needed for adult Philadelphia chromosome-positive acute lymphoblastic leukemia receiving tyrosine kinase inhibitors therapy?: A systematic review and meta-analysis

BACKGROUND: Hematopoietic stem cell transplantation (HSCT) is the current mainstay treatment for Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph(+) ALL). However, tyrosine kinase inhibitors (TKI) also play a significant role in the treatment of these patients. We conducted this sys...

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Detalles Bibliográficos
Autores principales: Ponvilawan, Ben, Kungwankiattichai, Smith, Charoenngam, Nipith, Owattanapanich, Weerapat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238225/
https://www.ncbi.nlm.nih.gov/pubmed/34181696
http://dx.doi.org/10.1371/journal.pone.0253896