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Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells

Background: Resistance to antiproliferative chemotherapies remains a significant challenge in the care of patients with solid tumors. Glucocorticoids, including endogenous cortisol, have been shown to induce pro-survival pathways in epithelial tumor cells. While pro-apoptotic effects of glucocortico...

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Detalles Bibliográficos
Autores principales: Greenstein, Andrew E., Hunt, Hazel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238250/
https://www.ncbi.nlm.nih.gov/pubmed/34194622
http://dx.doi.org/10.18632/oncotarget.27989