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Rapid Evolution of Autosomal Binding Sites of the Dosage Compensation Complex in Drosophila melanogaster and Its Association With Transcription Divergence

How pleiotropy influences evolution of protein sequence remains unclear. The male-specific lethal (MSL) complex in Drosophila mediates dosage compensation by 2-fold upregulation of the X chromosome in males. Nevertheless, several MSL proteins also bind autosomes and likely perform functions not rela...

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Detalles Bibliográficos
Autores principales: Dai, Aimei, Wang, Yushuai, Greenberg, Anthony, Liufu, Zhongqi, Tang, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238462/
https://www.ncbi.nlm.nih.gov/pubmed/34194473
http://dx.doi.org/10.3389/fgene.2021.675027