Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancer

Chemotherapy resistance is a critical barrier in cancer treatment. Metabolic adaptations have been shown to fuel therapy resistance; however, little is known regarding the generality of these changes and whether specific therapies elicit unique metabolic alterations. Using a combination of metabolom...

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Detalles Bibliográficos
Autores principales: McGuirk, Shawn, Audet-Delage, Yannick, Annis, Matthew G, Xue, Yibo, Vernier, Mathieu, Zhao, Kaiqiong, St-Louis, Catherine, Minarrieta, Lucía, Patten, David A, Morin, Geneviève, Greenwood, Celia MT, Giguère, Vincent, Huang, Sidong, Siegel, Peter M, St-Pierre, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238502/
https://www.ncbi.nlm.nih.gov/pubmed/34181531
http://dx.doi.org/10.7554/eLife.65150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238502/
https://www.ncbi.nlm.nih.gov/pubmed/34181531
http://dx.doi.org/10.7554/eLife.65150

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