Autophagic Degradation of Gasdermin D Protects against Nucleus Pulposus Cell Pyroptosis and Retards Intervertebral Disc Degeneration In Vivo

Intervertebral disc degeneration (IDD) is the primary culprit of low back pain and renders heavy social burden worldwide. Pyroptosis is a newly discovered form of programmed cell death, which is also involved in nucleus pulposus (NP) cells during IDD progression. Moderate autophagy activity is criti...

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Detalles Bibliográficos
Autores principales: Liao, Zhiwei, Li, Suyun, Liu, Rong, Feng, Xiaobo, Shi, Yunsong, Wang, Kun, Li, Shuai, Zhang, Yukun, Wu, Xinghuo, Yang, Cao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238599/
https://www.ncbi.nlm.nih.gov/pubmed/34239691
http://dx.doi.org/10.1155/2021/5584447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238599/
https://www.ncbi.nlm.nih.gov/pubmed/34239691
http://dx.doi.org/10.1155/2021/5584447

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