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Resveratrol Alleviates 27-Hydroxycholesterol-Induced Senescence in Nerve Cells and Affects Zebrafish Locomotor Behavior via Activation of SIRT1-Mediated STAT3 Signaling

The oxysterol 27-hydroxycholesterol (27HC) is the first identified endogenous selective estrogen receptor modulator (SERM), which like endogenous estrogen 17β-estradiol (E(2)) induces the proliferation of estrogen receptor- (ER-) positive breast cancer cells in vitro. However, 27HC differs from E(2)...

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Detalles Bibliográficos
Autores principales: Liu, Jiao, Jiao, Kailin, Zhou, Qian, Yang, Jun, Yang, Keke, Hu, Chunyan, Zhou, Ming, Li, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238615/
https://www.ncbi.nlm.nih.gov/pubmed/34239694
http://dx.doi.org/10.1155/2021/6673343