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Antimycobacterial Activity, Synergism, and Mechanism of Action Evaluation of Novel Polycyclic Amines against Mycobacterium tuberculosis

Mycobacterium tuberculosis has developed extensive resistance to numerous antimycobacterial agents used in the treatment of tuberculosis. Insufficient intracellular accumulation of active moieties allows for selective survival of mycobacteria with drug resistance mutations and accordingly promotes t...

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Detalles Bibliográficos
Autores principales: Kapp, Erika, Joubert, Jacques, Sampson, Samantha L., Warner, Digby F., Seldon, Ronnett, Jordaan, Audrey, de Vos, Margaretha, Sharma, Rajan, Malan, Sarel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238621/
https://www.ncbi.nlm.nih.gov/pubmed/34240057
http://dx.doi.org/10.1155/2021/5583342