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Oocyte-specific gene knockdown by intronic artificial microRNAs driven by Zp3 transcription in mice

Conditional knockout technology is a powerful tool for investigating the spatiotemporal functions of target genes. However, generation of conditional knockout mice involves complicated breeding programs and considerable time. A recent study has shown that artificially designed microRNAs (amiRNAs), i...

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Detalles Bibliográficos
Autores principales: SASAKI, Keisuke, TAKAOKA, Saaya, OBATA, Yayoi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238676/
https://www.ncbi.nlm.nih.gov/pubmed/33716236
http://dx.doi.org/10.1262/jrd.2020-146