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Shifting the paradigms for tumor suppression: lessons from the p53 field

The TP53 gene continues to hold distinction as the most frequently mutated gene in cancer. Since its discovery in 1979, hundreds of research groups have devoted their efforts toward understanding why this gene is so frequently selected against by tumors, with the hopes of harnessing this information...

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Detalles Bibliográficos
Autores principales: Barnoud, Thibaut, Indeglia, Alexandra, Murphy, Maureen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238873/
https://www.ncbi.nlm.nih.gov/pubmed/34103683
http://dx.doi.org/10.1038/s41388-021-01852-z