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MYD88, NFKB1, and IL6 transcripts overexpression are associated with poor outcomes and short survival in neonatal sepsis

Toll-like receptor (TLR) family signature has been implicated in sepsis etiopathology. We aimed to evaluate the genetic profile of TLR pathway-related key genes; the myeloid differentiation protein 88 (MYD88), IL1 receptor-associated kinase 1 (IRAK1), the nuclear factor kappa-B1 (NFKB1), and interle...

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Detalles Bibliográficos
Autores principales: AbdAllah, Nouran B., Toraih, Eman A., Al Ageeli, Essam, Elhagrasy, Hala, Gouda, Nawal S., Fawzy, Manal S., Helal, Ghada M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8238937/
https://www.ncbi.nlm.nih.gov/pubmed/34183713
http://dx.doi.org/10.1038/s41598-021-92912-7